Category: Research Article
Gastroschisis and Related Disruptive Disorders Associated with Amyoplasia: Implications for Decreased Maternal Age Effects, Increasing Rates, and Pathogenetic Heterogeneity
Introduction: Gastroschisis and amyoplasia are disruptive disorders that are usually found separately, but that can occasionally associate. Their relationship is examined to help understand the…
Probiotics/ Prebiotics/ Synbiotic Supplementation in Reducing the Severity of Gastroenteritis among Children of 0-12 Years Age
This systematic review evaluates all clinical studies that cumulatively analyse how the use of probiotics, prebiotics or symbiotic have reduced the severity of gastroenteritis (GE)…
Intra Uterine Growth Restriction and Related Risk Factors
Background: Intrauterine growth restriction (IUGR) increases the morbidity and mortality of neonates, which is a major public health problem. Predictive factors such as hypertension, diabetes,…
Applicability of a Tool for Comprehensive Pediatric Assessments: The Expanded Guide for Monitoring Child Development
Background: Tools that provide comprehensive information about children and families without increasing face-to-face time during healthcare encounters are critically needed in clinical practice. We aimed…
Characteristics of Postpartum Japanese Mothers Who Were Nonrespondents to the Japan Environment and Children’s Study
Background: This study aimed to examine the factors behind survey non-response in mothers who had agreed to participate in a Japanese nationwide birth cohort study-…
Analysis of Follow-Up Results after Successful Conservative Treatment of Pediatric Appendiceal Abscess- A Single Institutional Retrospective Study
Purpose: The follow-up results of successful conservative treatment of appendiceal abscess in children were analyzed to further explore the value of interval appendectomy (IA).Method: Follow-up…
Periconceptional Maternal Folic Acid Supplementation Mediate DNA Methylation Affecting Off spring Health
Folate, VitB12, choline, betaine and methionine both participate in the one-carbon metabolism (FOCM). Under the action of FOCM cycle enzymes, above-mentioned micronutrients convert to essential…
Aspirin Responsive Sticky Platelet Mediated Thrombophilia Caused by Gain of Function Mutations in the Thrombopoietin, JAK2 and MPL Genes in Hereditary and Acquired Essential Thrombocythemia
In the 1990s it was known that thrombopoietin (TPO) stimulates megakaryocyte production both in vitro and in vivo [1-3]. Size, number, and mean geometric ploidy…
Genetic Testing and Neurodevelopmental Follow Up in Patients with Conotruncal Abnormalities
Congenital heart disease (CHD) is the most common birth defect and in most cases idiopathic. Genetic causes account for up to 35% of patients with…
Development of a Questionnaire Method of Screening for Citrin Deficiency in Schoolchildren
Citrin deficiency is one of the most frequent diseases among congenital metabolic disorders in Japan. Based on the time of its onset, citrin deficiency is…
